Research proves that Cannabis Prevents the Spread of HIV but Scientists are developing new drugs using cannabinioids to benefit the pharmaceutical industry.
The awe-inspiring verification of the therapeutic abilities of cannabis and cannabinoids put a little ambiguity that the pharmaceutical industry is the reason of cannabis criminalization laws. A lot of researches now certifying the factual noteworthy nature of this curative plant are just amazing
The U.S. Patent 6630507 was purposely prefer by researchers who found that cannabinoids had clear-cut antioxidant powers that makes them helpful in curing and prophylaxis of broad range of oxidation-associated ailments, such as ischemic, age-related, inflammatory and autoimmune diseases. Cannabinoids are studied that it can seemingly perform certain functions such as neuro-protectants, for instance in preventing neurological break down following ischemic insults, such as stroke and trauma, or in dealing with the neurodegenerative illness such as Alzheimer’s illness, Parkinson’s illness and HIV dementia.
One more U.S Patent 20130059018 was examined revealed the invention that cannabinoids avert cancer cells from isolating and proliferating. According to the reports of the patent “cannabinoids, together with THC and Cannabidiol, encourage the recurrence of apoptosis so that cancer cells will prevent from isolating and die”. Netherlands is the first country who supported cannabis to make it easily accessible as a medicine in pharmacies to treat different types of cancer, as well as multiple sclerosis and HIV patients.
Cannabis averts the Spread of HIV
From the journal PLoS ONE findings, examiners have affirmed that cannabis extracts activate receptors of human immune cells that can directly impede a form of human immuno-deficiency virus (HIV) found in late-stage AIDS.
Therapeutic cannabis has been naturally approved to soothe pain, debilitating weight loss and craving control in sufferers with advanced AIDS. Mount Sinai School of Medicine examiners have performed the first research to expose how the cannabis receptors present in immune cells — called cannabinoid receptors CB1 and CB2 — can control the multiplication of the disease.
Cannabis researcher and activist Jason Mihaldas says the research ultimately defend what the pro-cannabis community has always acknowledged;
“Decades of anecdotal and experimental facts are now being authorized by the scientific community, but they are regrettably using this examination for their own egotistic aims — to take cannabis from its raw therapeutically effectual form to one where it will be therapeutically useless with chemical agents, changing what it was naturally made to … heal”.
Sadly, the scientists cruelly use the exploration on the curative properties of these receptors to boost the production new drugs to assist the pharmaceutical industry.
‘It is well-known to us that cannabinoid from cannabis can have a remedial impact in AIDS sufferers, but did not figure out how they control the multiplication of the disease itself,’ said research author Cristina Costantino, PhD, Postdoctoral Fellow in the Department of Pharmacology and Systems Therapeutics at Mount Sinai School of Medicine. ‘We are required to discover cannabinoid receptors as a goal for pharmaceutical progression that cure the signs of final-stage AIDS and avert additional succession of the ailment without the unwanted side effects of medical cannabis’.
HIV passes on a disease to active immune cells that transmit the viral receptor CD4, which makes these cells incapable to battle off the disease. In order to increase, the disease need that “resting” immune cells be activated. In advanced AIDS, HIV mutates so it can contaminate these resting cells, attaining access into the cell by using an indicator receptor called CXCR4. When cells are treated by a cannabinoid agonist it activates CB2, Dr. Costantino and the Mount Sinai team examined that CB2 hinders the signalling progression, and suppressed infection in resting immune cells.Nonpsychoactive cannabinoids, such as cannabidoil, are particularly advantageous to use because they avoid toxicity that is encountered with psychoactive cannabinoids at high doses useful in the method of the present invention. CBD (Cannabidiol), one of the chief ingredients of the marijuana plant has been verified therapeutically to alleviate countless ailments together with the inhibition of cancer cell development. Current studies have exposed it to be a valuable atypical anti-psychotic in curing schizophrenia. CBD also hamper with the quantity of THC your brain processes, balancing the psychotropic effect of marijuana. That is exactly why the curative influence of raw marijuana is increasing rapidly.
The Mount Sinai team contaminated healthy immune cells with HIV, and then treated them with a compound that activates CB2 called an agonist. They examined that the drug decrease the infection of the left over cells.
Creating a drug that activates only CB2 as an adjunctive treatment to standard anti-viral prescription may assist to lessen the signs of late-stage AIDS and stop the disease from spreading,” said Dr. Costantino. Because HIV does not use CXCR4 to augment immune cell contamination in the premature stages of infection, CB2 agonists emerging to be a helpful antiviral medicine only in late-stage ailment.
As an outcome of this findings, the examiners team guided by Benjamin Chen, MD, PhD, Associate Professor of Infectious Diseases, and Lakshmi Devi, PhD, Professor of Pharmacology and Systems Therapeutics at Mount Sinai School of Medicine, develop a strategy to test a mouse model of late-stage AIDS in order to investigate the effectiveness of a drug that activates CB2 in vivo.
At present the scientific data is being made public, an intensive attempt must be made from all states to stop cannabis-criminalization laws. Using or possessing a plant should never be considered as unlawful crime and the mutual ravenousness at the foundation of these laws is now coming to light.